{"id":165,"date":"2021-06-27T00:22:23","date_gmt":"2021-06-27T03:22:23","guid":{"rendered":"http:\/\/biobreyer.com.br\/?page_id=165"},"modified":"2022-07-07T16:58:00","modified_gmt":"2022-07-07T19:58:00","slug":"asparaginase","status":"publish","type":"page","link":"https:\/\/biobreyer.com.br\/en\/asparaginase\/","title":{"rendered":"Asparaginase"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Hero&#8221; _builder_version=&#8221;4.17.4&#8243; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2022\/06\/asparaginase-header-img.jpg&#8221; custom_margin=&#8221;75px||||false|false&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;55px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;||||false|false&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;|700|||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;40px&#8221; header_text_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;120px||120px||false|false&#8221; text_font_size_tablet=&#8221;&#8221; text_font_size_phone=&#8221;30px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span>ASPARAGINASE<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; admin_label=&#8221;About Us Section&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#fafbfc&#8221; custom_padding=&#8221;100px|0px|49px|0px|false|false&#8221; custom_padding_tablet=&#8221;100px|0px|49px|0px|false|false&#8221; custom_padding_phone=&#8221;50px|0px|50px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;|||&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; header_font=&#8221;||||||||&#8221; header_3_font=&#8221;IBM Plex Sans|600|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#4c4b55&#8243; header_3_font_size=&#8221;40px&#8221; custom_margin=&#8221;0px|0px|0px|0px|false|false&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|false&#8221; header_3_font_size_tablet=&#8221;40px&#8221; header_3_font_size_phone=&#8221;30px&#8221; header_3_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Innovative biopharmaceutical with 100% national technology<\/h3>\n<p>[\/et_pb_text][et_pb_divider divider_position=&#8221;center&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;90px&#8221; max_width_tablet=&#8221;13%&#8221; max_width_last_edited=&#8221;off|desktop&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;10px||10px||false|false&#8221; 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global_colors_info=&#8221;{}&#8221;]<\/p>\n<p class=\" translation-block\"><strong>BIOBREYER<\/strong> develops a biosuperior biopharmaceutical for the treatment of Acute Lymphoblastic Leukemia. Our Asparaginase molecule is more stable and less immunogenic, having the ability to provide a better quality treatment. We are currently scaling up the production and carrying out pre-clinical trials.<\/p>\n<p>The scaling up of the production process was carried out in order to cover all stages of the process: from the cell bank to the final formulation. We have developed an innovative upstream process and for downstream stages we rely on the consultancy of the company Merck.<\/p>\n<p>The pre-clinical trials are being carried out in partnership with Hospital das Cl\u00ednicas and the USP School of Medicine and involve experiments with leukemic cells from patients, mice and zebrafish embryos.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2021\/06\/Asparaginase-sem-superficie2.png&#8221; title_text=&#8221;Asparaginase-sem-superficie2&#8243; align_tablet=&#8221;center&#8221; align_phone=&#8221;center&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; animation_style=&#8221;fade&#8221; custom_css_main_element=&#8221; 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image_icon_background_color=&#8221;RGBA(255,255,255,0)&#8221; image=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2022\/06\/icon1.png&#8221; image_icon_width=&#8221;60%&#8221; admin_label=&#8221;Class&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;IBM Plex Sans|600||on|||||&#8221; header_text_align=&#8221;center&#8221; header_text_color=&#8221;#4c4b55&#8243; header_font_size=&#8221;18px&#8221; header_line_height=&#8221;1.3em&#8221; body_font=&#8221;IBM Plex Sans||||||||&#8221; body_text_align=&#8221;center&#8221; body_text_color=&#8221;#4c4b55&#8243; body_font_size=&#8221;16px&#8221; body_line_height=&#8221;1.8em&#8221; background_color=&#8221;#ffffff&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;40px|30px|40px|30px&#8221; animation_style=&#8221;fade&#8221; animation=&#8221;off&#8221; header_font_size_tablet=&#8221;18px&#8221; header_font_size_phone=&#8221;17px&#8221; header_font_size_last_edited=&#8221;on|phone&#8221; body_font_size_tablet=&#8221;16px&#8221; body_font_size_phone=&#8221;15px&#8221; body_font_size_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|6px|6px|6px|6px&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;10px&#8221; box_shadow_blur=&#8221;24px&#8221; box_shadow_spread=&#8221;6px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.06)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Protein with structural modifications that provide a longer half-life in the bloodstream and lower antibody formation.<\/br><\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;tecnologia 100% nacional&#8221; image_icon_background_color=&#8221;RGBA(255,255,255,0)&#8221; image=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2022\/06\/icon2.png&#8221; 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border_radii=&#8221;on|6px|6px|6px|6px&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;10px&#8221; box_shadow_blur=&#8221;24px&#8221; box_shadow_spread=&#8221;6px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.06)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>All technology related to the molecule and the production process is 100% national.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.17.3&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;inova\u00e7\u00e3o global&#8221; image_icon_background_color=&#8221;RGBA(255,255,255,0)&#8221; image=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2022\/06\/icon3.png&#8221; image_icon_width=&#8221;60%&#8221; admin_label=&#8221;Class&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;IBM Plex Sans|600||on|||||&#8221; header_text_align=&#8221;center&#8221; 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background_layout=&#8221;dark&#8221; custom_margin=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>REQUEST YOUR QUOTATION<\/h3>\n<p>Fill out the form below so that our sales team can contact you and offer the best product.<\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2022\/06\/solicita-orcamento-tecnologias.jpg&#8221; title_text=&#8221;solicita-or\u00e7amento-tecnologias&#8221; show_in_lightbox=&#8221;on&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.17.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;align-self: center;&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_contact_form use_spam_service=&#8221;on&#8221; recaptcha_list=&#8221;Biobreyer|Biobreyer-0&#8243; email=&#8221;contato@biobreyer.com.br&#8221; success_message=&#8221;Sua Mensagem foi enviada com sucesso!&#8221; submit_button_text=&#8221;ENVIAR&#8221; module_id=&#8221;et_pb_contact_form_0&#8243; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; form_field_font=&#8221;IBM Plex Sans||||||||&#8221; form_field_font_size=&#8221;14px&#8221; custom_button=&#8221;on&#8221; button_text_size=&#8221;17px&#8221; button_text_color=&#8221;#ffffff&#8221; button_bg_color=&#8221;#a90c25&#8243; button_border_width=&#8221;0px&#8221; button_border_color=&#8221;RGBA(255,255,255,0)&#8221; button_border_radius=&#8221;5px&#8221; button_font=&#8221;IBM Plex Sans|600||on|||||&#8221; button_use_icon=&#8221;off&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;|||&#8221; button_text_size_tablet=&#8221;17px&#8221; button_text_size_phone=&#8221;14px&#8221; button_text_size_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|6px|6px|6px|6px&#8221; box_shadow_style=&#8221;preset1&#8243; 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