{"id":165,"date":"2021-06-27T00:22:23","date_gmt":"2021-06-27T03:22:23","guid":{"rendered":"http:\/\/biobreyer.com.br\/?page_id=165"},"modified":"2022-07-07T16:58:00","modified_gmt":"2022-07-07T19:58:00","slug":"asparaginase","status":"publish","type":"page","link":"https:\/\/biobreyer.com.br\/es\/asparaginase\/","title":{"rendered":"Asparaginasa"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Hero&#8221; _builder_version=&#8221;4.17.4&#8243; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2022\/06\/asparaginase-header-img.jpg&#8221; custom_margin=&#8221;75px||||false|false&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;55px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;||||false|false&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;|700|||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;40px&#8221; header_text_color=&#8221;#FFFFFF&#8221; custom_padding=&#8221;120px||120px||false|false&#8221; text_font_size_tablet=&#8221;&#8221; text_font_size_phone=&#8221;30px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span>ASPARAGINASA<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; admin_label=&#8221;About Us Section&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#fafbfc&#8221; custom_padding=&#8221;100px|0px|49px|0px|false|false&#8221; custom_padding_tablet=&#8221;100px|0px|49px|0px|false|false&#8221; custom_padding_phone=&#8221;50px|0px|50px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;|||&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; header_font=&#8221;||||||||&#8221; header_3_font=&#8221;IBM Plex Sans|600|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#4c4b55&#8243; header_3_font_size=&#8221;40px&#8221; custom_margin=&#8221;0px|0px|0px|0px|false|false&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|false&#8221; header_3_font_size_tablet=&#8221;40px&#8221; header_3_font_size_phone=&#8221;30px&#8221; header_3_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Biof\u00e1rmaco innovador con tecnolog\u00eda 100% nacional<\/h3>\n<p>[\/et_pb_text][et_pb_divider divider_position=&#8221;center&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;90px&#8221; max_width_tablet=&#8221;13%&#8221; max_width_last_edited=&#8221;off|desktop&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;10px||10px||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; header_font=&#8221;||||||||&#8221; header_3_font=&#8221;IBM Plex Sans|600|||||||&#8221; header_3_text_color=&#8221;#a90c25&#8243; header_3_font_size=&#8221;36px&#8221; header_3_line_height=&#8221;1.4em&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;0px||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;||||false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; header_3_font_size_tablet=&#8221;36px&#8221; header_3_font_size_phone=&#8221;30px&#8221; header_3_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Asparaginasa<\/h3>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;IBM Plex Sans||||||||&#8221; text_text_color=&#8221;#4c4b55&#8243; text_font_size=&#8221;15px&#8221; text_line_height=&#8221;1.8em&#8221; header_font=&#8221;||||||||&#8221; custom_margin=&#8221;||||false|false&#8221; text_font_size_tablet=&#8221;15px&#8221; text_font_size_phone=&#8221;14px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; text_line_height_tablet=&#8221;1.8em&#8221; text_line_height_phone=&#8221;1.8em&#8221; text_line_height_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p class=\" translation-block\"><strong>BIOBREYER<\/strong> desarrolla un biof\u00e1rmaco biosuperior para el tratamiento de leucemia linfobl\u00e1stica aguda. Nuestra mol\u00e9cula de Asparaginasa es m\u00e1s estable y menos inmunog\u00e9nica, lo cual permite brindar un tratamiento de mejor calidad. Actualmente estamos realizado el escalado de la producci\u00f3n y ensayos precl\u00ednicos.<\/p>\n<p>El escalado del proceso de producci\u00f3n se realiz\u00f3  pensando en cada una de las etapas del proceso: desde la creaci\u00f3n del banco de c\u00e9lulas hasta la formulaci\u00f3n final.\nPara nuestro biof\u00e1rmaco hemos desarrollado un proceso de upstream innovador. Por otro lado, las etapas downstream las hemos montado con base en una consultor\u00eda de la empresa Merck.<\/p>\n<p>Los ensayos precl\u00ednicos se est\u00e1n realizando en colaboraci\u00f3n con el Hospital das Cl\u00ednicas y la Facultad de Medicina de la Universidade de S\u00e3o Paulo - USP y engloban experimentos con c\u00e9lulas leuc\u00e9micas de pacientes, ratones y embriones de zebrafish.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2021\/06\/Asparaginase-sem-superficie2.png&#8221; title_text=&#8221;Asparaginase-sem-superficie2&#8243; align_tablet=&#8221;center&#8221; align_phone=&#8221;center&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; 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header_font_size_phone=&#8221;17px&#8221; header_font_size_last_edited=&#8221;on|phone&#8221; body_font_size_tablet=&#8221;16px&#8221; body_font_size_phone=&#8221;15px&#8221; body_font_size_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|6px|6px|6px|6px&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;10px&#8221; box_shadow_blur=&#8221;24px&#8221; box_shadow_spread=&#8221;6px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.06)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Prote\u00edna con modificaciones estructurales las cuales proporcionan un aumento en el tiempo de vida media en el torrente sangu\u00edneo y una menor formaci\u00f3n de anticuerpos.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;tecnologia 100% nacional&#8221; image_icon_background_color=&#8221;RGBA(255,255,255,0)&#8221; image=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2022\/06\/icon2.png&#8221; image_icon_width=&#8221;60%&#8221; admin_label=&#8221;Class&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;IBM Plex Sans|600||on|||||&#8221; header_text_align=&#8221;center&#8221; header_text_color=&#8221;#4c4b55&#8243; header_font_size=&#8221;18px&#8221; header_line_height=&#8221;1.3em&#8221; body_font=&#8221;IBM Plex Sans||||||||&#8221; body_text_align=&#8221;center&#8221; body_text_color=&#8221;#4c4b55&#8243; body_font_size=&#8221;16px&#8221; body_line_height=&#8221;1.8em&#8221; background_color=&#8221;#ffffff&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;40px|30px|97px|30px|false|false&#8221; animation_style=&#8221;fade&#8221; animation=&#8221;off&#8221; header_font_size_tablet=&#8221;18px&#8221; header_font_size_phone=&#8221;17px&#8221; header_font_size_last_edited=&#8221;on|phone&#8221; body_font_size_tablet=&#8221;16px&#8221; body_font_size_phone=&#8221;15px&#8221; body_font_size_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|6px|6px|6px|6px&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;10px&#8221; box_shadow_blur=&#8221;24px&#8221; box_shadow_spread=&#8221;6px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.06)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Toda la tecnolog\u00eda relacionada con la mol\u00e9cula y el proceso de producci\u00f3n es 100% nacional.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.17.3&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;inova\u00e7\u00e3o global&#8221; image_icon_background_color=&#8221;RGBA(255,255,255,0)&#8221; image=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2022\/06\/icon3.png&#8221; image_icon_width=&#8221;60%&#8221; admin_label=&#8221;Class&#8221; _builder_version=&#8221;4.17.4&#8243; 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box_shadow_blur=&#8221;24px&#8221; box_shadow_spread=&#8221;6px&#8221; box_shadow_color=&#8221;rgba(0,0,0,0.06)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Nuestra mol\u00e9cula tiene caracter\u00edsticas \u00fanicas que la hacen diferente a lo que se ofrece en el mercado actual.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;on|off|off&#8221; admin_label=&#8221;Become a Member Section&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; custom_padding=&#8221;50px|0px|50px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; admin_label=&#8221;Call to Action&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; 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header_font=&#8221;||||||||&#8221; header_text_color=&#8221;#ffffff&#8221; header_font_size=&#8221;24px&#8221; header_3_font=&#8221;IBM Plex Sans|700||on|||||&#8221; header_3_text_color=&#8221;#a90c25&#8243; header_3_font_size=&#8221;36px&#8221; header_3_line_height=&#8221;1.4em&#8221; background_layout=&#8221;dark&#8221; custom_margin=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>SOLICITE SU COTIZACI\u00d3N<\/h3>\n<p>Preencha o formul\u00e1rio abaixo para que nossa equipe comercial entre em contato e ofere\u00e7a o melhor produto.[\/et_pb_text][et_pb_contact_form use_spam_service=&#8221;on&#8221; recaptcha_list=&#8221;Biobreyer|Biobreyer-0&#8243; email=&#8221;contato@biobreyer.com.br&#8221; success_message=&#8221;Sua Mensagem foi enviada com sucesso!&#8221; submit_button_text=&#8221;ENVIAR&#8221; module_id=&#8221;et_pb_contact_form_0&#8243; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; form_field_font=&#8221;IBM Plex Sans||||||||&#8221; 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background_layout=&#8221;dark&#8221; custom_margin=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>SOLICITE SU COTIZACI\u00d3N<\/h3>\n<p>Llene el siguiente formulario para que nuestro equipo comercial se pueda contactar con usted y ofrecerle el mejor producto.<\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/biobreyer.com.br\/wp-content\/uploads\/2022\/06\/solicita-orcamento-tecnologias.jpg&#8221; title_text=&#8221;solicita-or\u00e7amento-tecnologias&#8221; show_in_lightbox=&#8221;on&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.17.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;align-self: center;&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_contact_form use_spam_service=&#8221;on&#8221; recaptcha_list=&#8221;Biobreyer|Biobreyer-0&#8243; 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disabled_on=&#8221;on|off|off&#8221; admin_label=&#8221;Join Now Call to Action&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;221deg&#8221; background_color_gradient_stops=&#8221;rgba(169,12,37,0.6) 0%|#a90c25 96%&#8221; background_color_gradient_start=&#8221;#1bb3eb&#8221; background_color_gradient_end=&#8221;#25efcb&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;70px|0px|70px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.17.3&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; 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